Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6529833 | 0.88 | NPC1 (0.59) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL8133353 | 0.88 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6528645 | 0.85 | TSHR (0.55) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6527832 | 0.82 | NPC1 (0.52) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL8116943 | 0.82 | TSHR (0.61) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL22808203 | 0.81 | TP53 (0.61) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL3831190 | 0.81 | SMN1; SMN2 (0.55) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6530208 | 0.81 | SYK (0.52) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL8125827 | 0.80 | TSHR (0.54) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL10305252 | 0.79 | ROCK2 (0.67) | NPC1ALDH1A1TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |
| EP-1049692-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | Bayer Aktiengesellschaft (DE) | 2000-11-08 | — | — | EP | disclosed |
| WO-1999037641-A1 | NOVEL BICYCLENE-SUBSTITUTED OXAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |