Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6527452 | 0.89 | NPC1 (0.51) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6529831 | 0.87 | NPC1 (0.48) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL3826565 | 0.83 | SMN1; SMN2 (0.47) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6532124 | 0.82 | NPC1 (0.60) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL5283837 | 0.76 | MGLL (0.50) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL8133353 | 0.75 | NPC1 (0.58) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL18787217 | 0.75 | PRKDC (0.57) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL3827643 | 0.74 | NPC1 (0.45) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL5286245 | 0.74 | MGLL (0.47) | NPC1ALDH1A1TP53MAPTTSHR | |
| SCHEMBL6210658 | 0.74 | NPC1 (0.48) | NPC1ALDH1A1TP53MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082897-A1 | OXAZOLIDINONE ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |