Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | DAPK1 | P53355 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1384073 | 0.81 | CNR2 (0.47) | PDE10AALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1387091 | 0.81 | MAOB (0.46) | PDE10AALDH1A1LMNAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL2579429 | 0.80 | CNR2 (0.46) | PDE10AALDH1A1LMNAHPGDTSHR | |
| Hydrochloric Acid SCHEMBL2581597 | 0.80 | MAOB (0.45) | PDE10AALDH1A1LMNAHPGDTSHR | |
| SCHEMBL1385049 | 0.79 | PDE10A (0.43) | PDE10ASQORGABRG2GABRB3GABRA1 | |
| Hydrochloric Acid SCHEMBL2577843 | 0.78 | PDE10A (0.42) | PDE10ASQORGABRG2GABRB3GABRA1 | |
| SCHEMBL1384547 | 0.78 | PDE10A (0.42) | PDE10ASQORGABRG2GABRB3GABRA1 | |
| Hydrochloric Acid SCHEMBL2575915 | 0.77 | POLB (0.42) | PDE10ASQORGABRG2GABRB3GABRA1 | |
| SCHEMBL1386845 | 0.77 | PDE10A (0.41) | PDE10AHTTSQORGABRG2GABRB3 | |
| SCHEMBL27666359 | 0.77 | SQOR (0.44) | PDE10AALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051917-A9 | PYRAZOLYL DERIVATIVES IN THE FORM OF DRUGS FOR TREATING ACUTE OR CHRONIC NEURONAL REGRESSIONS | AVENTIS PHARMA SA (FR) | 2005-09-29 | — | — | WO | claimed |