Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | GSTP1 | P09211 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761531 | 0.86 | GABRA1 (0.39) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL6530521 | 0.85 | ACHE (0.47) | CNR1ACHECNR2LMNAHPGD | |
| SCHEMBL1387091 | 0.84 | MAOB (0.46) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| Hydrochloric Acid SCHEMBL2581597 | 0.83 | MAOB (0.45) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL27666373 | 0.82 | ENPP2 (0.48) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL1385049 | 0.80 | PDE10A (0.43) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL1385833 | 0.79 | LTA4H (0.48) | L3MBTL1ALDH1A1HTT | |
| Hydrochloric Acid SCHEMBL2577843 | 0.79 | PDE10A (0.42) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| SCHEMBL1384547 | 0.79 | PDE10A (0.42) | SQORGABRG2GABRB3GABRA5GABRA1 | |
| Hydrochloric Acid SCHEMBL2575915 | 0.78 | POLB (0.42) | SQORGABRG2GABRB3GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102174017-A | Pyrazolyl derivatives in the form of drugs for treating acute or chronic neuronal regressions | AVENTIS PHARMA SA | 2011-09-07 | — | — | CN | disclosed |
| CN-1906172-A | Pyrazole derivatives as medicaments for the treatment of acute or chronic neuronal degeneration | AVENTIS PHARMA SA (FR) | 2007-01-31 | — | — | CN | disclosed |