Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1082979 | 0.85 | BRD4 (0.39) | BRD4KDM4EALDH1A1 | |
| SCHEMBL1082814 | 0.82 | DAO (0.37) | KMT2ADAOCASP1HSD17B10MAPT | |
| SCHEMBL3802743 | 0.81 | DAO (0.42) | MEN1KMT2ADAOMAPT | |
| SCHEMBL6287877 | 0.81 | HTR4 (0.41) | KMT2ADAOKDM4ECASP1 | |
| SCHEMBL1082600 | 0.80 | BRD4 (0.44) | MEN1KMT2ABRD4LMNANPSR1 | |
| SCHEMBL3807621 | 0.80 | DAO (0.38) | KMT2ABRD4DAOCASP1HSD17B10 | |
| SCHEMBL1082511 | 0.79 | DAO (0.37) | MEN1KMT2ADAOKDM4ECASP1 | |
| SCHEMBL1082159 | 0.78 | DAO (0.36) | KMT2ADAOKDM4ECASP1HSD17B10 | |
| SCHEMBL1081504 | 0.75 | SIGMAR1 (0.39) | DAOKDM4EALDH1A1 | |
| SCHEMBL1082822 | 0.74 | SIGMAR1 (0.41) | MEN1KMT2ADAOKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560827-A1 | ANTI-INFECTIVE AGENTS | Abbott Laboratories (US) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |