Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8503990 | 0.84 | CYP1A2 (0.70) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL6856046 | 0.84 | CYP1A2 (0.54) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL7206606 | 0.80 | CYP1A2 (0.56) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL12803074 | 0.80 | HRH1 (0.57) | CYP1A2CYP2C19HRH1TDP1ALOX15 | |
| SCHEMBL29631825 | 0.80 | HRH1 (0.57) | CYP1A2CYP2C19HRH1TDP1ALOX15 | |
| SCHEMBL27461429 | 0.79 | CYP1A2 (0.55) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL2201641 | 0.78 | CYP1A2 (0.55) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL13859429 | 0.78 | CYP1A2 (0.50) | CYP1A2CYP2C19HRH1ALOX15LMNA | |
| SCHEMBL2452835 | 0.77 | CYP1A2 (0.57) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 | |
| SCHEMBL30925300 | 0.77 | CYP1A2 (0.57) | CYP1A2SMN1; SMN2CYP2C19HRH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030735-A1 | TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | claimed |