Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | CCR4 | P51679 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532488 | 0.92 | CA12 (0.46) | RAB9AFSCN1CNR2CCR4HDAC3 | |
| SCHEMBL1273700 | 0.85 | ALDH1A1 (0.56) | ALDH1A1CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL1273703 | 0.82 | POLB (0.47) | ALDH1A1CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL1273674 | 0.81 | PTGER4 (0.46) | ALDH1A1CYP2C9CYP2C19CCR4GAA | |
| SCHEMBL4250971 | 0.81 | CNR1 (0.46) | ALDH1A1CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL1273873 | 0.81 | GLA (0.64) | ALDH1A1RAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL1273710 | 0.81 | GLA (0.48) | ALDH1A1CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL4250973 | 0.80 | PHOSPHO1 (0.45) | ALDH1A1CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL3431653 | 0.78 | NPC1 (0.52) | ALDH1A1CYP2C9CYP2C19RAB9ANPC1 | |
| SCHEMBL1273266 | 0.78 | MAPT (0.61) | ALDH1A1CYP2C9CYP2C19HPGDFSCN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056532-A1 | INDAZOLE DERIVATIVES WHICH INTERACT WITH THE G-PROTEIN COUPLED RECEPTOR FAMILY | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-06-23 | — | — | WO | claimed |