Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 12/20 | 0.46 |
| ▸ | CA9 | Q16790 | 12/20 | 0.46 |
| ▸ | CA1 | P00915 | 7/20 | 0.45 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532344 | 0.92 | ALDH1A1 (0.48) | FSCN1CCR4HDAC3HDAC1HDAC2 | |
| SCHEMBL1273266 | 0.85 | MAPT (0.61) | CA12CA9CA1FSCN1MAPT | |
| SCHEMBL1273704 | 0.85 | ALDH1A1 (0.46) | CA12CA9CA1MAPTPOLB | |
| SCHEMBL1273818 | 0.84 | MAPT (0.44) | CA12CA9CA1FSCN1MAPT | |
| SCHEMBL1274226 | 0.83 | MAPT (0.54) | CA12CA9CA1MAPTPOLB | |
| SCHEMBL1274203 | 0.83 | POLB (0.46) | CCR4MAPTPOLBKMT2A | |
| SCHEMBL1273828 | 0.82 | POLB (0.46) | CA12CA9CCR4MAPTPOLB | |
| SCHEMBL4245639 | 0.82 | CA12 (0.45) | CA12CA9CA1HDAC3HDAC1 | |
| SCHEMBL1273830 | 0.81 | GLA (0.41) | CA12CA9CA1FSCN1MAPT | |
| SCHEMBL1273733 | 0.81 | GLA (0.55) | MAPTPOLBMEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056532-A1 | INDAZOLE DERIVATIVES WHICH INTERACT WITH THE G-PROTEIN COUPLED RECEPTOR FAMILY | BIOFOCUS DISCOVERY LIMITED (GB) | 2005-06-23 | — | — | WO | claimed |