Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5930725 | 0.93 | MAPT (0.42) | MAPTALDH1A1SMN1; SMN2TP53AKR1C3 | |
| SCHEMBL5930759 | 0.92 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2AKR1C3PDK1 | |
| SCHEMBL5930774 | 0.92 | ALDH1A1 (0.37) | MAPTALDH1A1SMN1; SMN2TP53AKR1C3 | |
| SCHEMBL4906499 | 0.86 | ALDH1A1 (0.48) | MAPTALDH1A1SMN1; SMN2TP53AKR1C3 | |
| SCHEMBL4894513 | 0.84 | HTT (0.48) | MAPTALDH1A1SMN1; SMN2TP53AKR1C3 | |
| SCHEMBL4899749 | 0.83 | ERBB2 (0.50) | MAPTALDH1A1SMN1; SMN2AKR1C3PKM | |
| SCHEMBL4895869 | 0.81 | MAPK1 (0.49) | MAPTALDH1A1SMN1; SMN2TP53PKM | |
| SCHEMBL6528721 | 0.80 | ALDH1A1 (0.47) | MAPTALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL6529960 | 0.79 | ALDH1A1 (0.40) | MAPTALDH1A1SMN1; SMN2TP53HTT | |
| SCHEMBL4905912 | 0.79 | MAPT (0.54) | MAPTTP53LMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER INC | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288340-A1 | Substituted heteroaryl- and phenylsulfamoyl compounds | PPARA, PPARG, PPARD | MAPT 1786/4885ALDH1A1 2956/4885SMN1; SMN2 3404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.