Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 12/20 | 0.42 |
| ▸ | PPARA | Q07869 | 7/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | MME | P08473 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | YAP1 | P46937 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532104 | 1.00 | LTA4H (0.43) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6532376 | 0.93 | LTA4H (0.43) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6532687 | 0.93 | LTA4H (0.43) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6532379 | 0.93 | LTA4H (0.43) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6532682 | 0.93 | LTA4H (0.43) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6533828 | 0.93 | LTA4H (0.42) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6533823 | 0.93 | LTA4H (0.42) | LTA4HPPARGPPARAATMMEN1 | |
| SCHEMBL6533887 | 0.90 | PPARG (0.39) | LTA4HPPARGPPARAATMNPC1 | |
| SCHEMBL6533884 | 0.90 | PPARG (0.39) | LTA4HPPARGPPARAATMNPC1 | |
| SCHEMBL6533237 | 0.87 | YAP1 (0.44) | LTA4HPPARGPPARAATMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |