Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.52 |
| ▸ | PPARA | Q07869 | 13/20 | 0.52 |
| ▸ | PPARG | P37231 | 6/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499481 | 0.82 | PPARD (0.60) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5023890 | 0.79 | PPARD (0.41) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5017243 | 0.74 | PPARD (0.60) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5015431 | 0.74 | PPARD (0.43) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6439387 | 0.74 | PPARD (0.55) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2528903 | 0.73 | PPARD (0.51) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL6438796 | 0.71 | PPARD (0.57) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL2465068 | 0.71 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5697537 | 0.71 | PPARD (0.71) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL3371056 | 0.71 | PPARD (0.55) | PPARDPPARAPPARGFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005060958-A1 | (5- (2-PHENYL)-THIAZOL-5-YLMETHOXY)-INDOL-1-YL) -ACETIC ACID DERIVATIVES AND RELATED COMPOUNDS AS MODULATORS OF THE HUMAN PPAR-DELTA RECEPTOR FOR THE TREATMENT OF METABOLIC DISORDERS SUCH AS TYPE 2 DIABETES | KALYPSYS, INC. (US) | 2005-07-07 | — | — | WO | disclosed |