Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 2/20 | 0.46 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024039 | 0.81 | KDM4E (0.54) | KMT2AALDH1A1POLB | |
| SCHEMBL2038892 | 0.77 | KMT2A (0.58) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL11438595 | 0.75 | MLKL (0.49) | KMT2ACYP2C9CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL11432513 | 0.73 | KMT2A (0.45) | KMT2ACYP2C9CYP3A4CYP2C19CYP1A2 | |
| SCHEMBL21247485 | 0.73 | CNR1 (0.43) | KMT2ACYP2C19CYP2D6 | |
| SCHEMBL29701262 | 0.72 | IDO1 (0.54) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL2937870 | 0.72 | TSHR (0.63) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL38663445 | 0.72 | BCHE (0.60) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL3842687 | 0.70 | KMT2A (0.61) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 | |
| SCHEMBL36603600 | 0.70 | KMT2A (0.61) | KMT2AALOX12CYP2C9CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1286673-B8 | LIGANDS OF INTEGRIN RECEPTORS | ABBOTT GMBH & CO KG (DE) | 2005-07-20 | — | — | EP | disclosed |
| EP-1286673-A2 | LIGANDS OF INTEGRIN RECEPTORS | Basf Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001093840-A2 | LIGANDS OF INTEGRIN RECEPTORS | BASF AG (DE) | 2001-12-13 | — | — | WO | disclosed |