Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 8/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCND1 | P24385 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 1/20 | 0.40 |
| ▸ | ATP4B | P51164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468053 | 0.77 | MAPK14 (0.45) | MAPK14MAOB | |
| SCHEMBL11970494 | 0.76 | MAPK14 (0.52) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL23969873 | 0.75 | MAPK14 (0.43) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL8106675 | 0.75 | ALDH1A1 (0.45) | MAPK14MAPK1ALPGPTK2B | |
| SCHEMBL271730 | 0.75 | MAPK14 (0.68) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL20386820 | 0.72 | MAPK14 (0.49) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL8100824 | 0.72 | MAPK14 (0.49) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL4478356 | 0.72 | MAPK14 (0.61) | MAPK14PTGS2L3MBTL1 | |
| SCHEMBL20382942 | 0.72 | MAPK14 (0.52) | MAPK14MAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL2363045 | 0.71 | GRM2 (0.67) | MAPK14MAPTMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | disclosed |