SCHEMBL6532750

SCHEMBL6532750

CN(C)c1ccc(C(O)c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.61
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
POLB P06746 1/20 0.61
ALDH1A1 P00352 5/20 0.56
KDM4E B2RXH2 2/20 0.56
HPGD P15428 2/20 0.53
MAPT P10636 2/20 0.53
SRD5A2 P31213 1/20 0.53
RAB9A P51151 3/20 0.52
TSHR P16473 2/20 0.50
HSD17B10 Q99714 1/20 0.50
RXRA P19793 1/20 0.49
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA2 P00918 1/20 0.49
CA9 Q16790 1/20 0.49
CA14 Q9ULX7 1/20 0.49
GAA P10253 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10866880 0.87 KMT2A (0.62) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL33368 0.86 NPC1 (0.77) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL28360958 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Hydrochloric Acid SCHEMBL1982376 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Ethane SCHEMBL3767932 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL10626135 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL2271443 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
SCHEMBL1552312 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1
Benzene SCHEMBL5410809 0.84 ALDH1A1 (0.52) NPC1KMT2AMEN1ALDH1A1KDM4E
Ammonia Solution, Strong SCHEMBL28138417 0.84 NPC1 (0.74) NPC1KMT2AMEN1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005105730-A2 METHOD OF PREPARING AN ALCOHOL FROM A HALOGENOAROMATIC COMPOUND AND AN ALDEHYDE SHASUN PHARMA SOLUTIONS LIMITED (GB) 2005-11-10 WO disclosed