SCHEMBL6532788

SCHEMBL6532788

O=C(O)c1c(Oc2ccc(Cl)cc2Cl)ccc2nc3ccccc3cc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.48
PLA2G1B P04054 1/20 0.48
ATG4B Q9Y4P1 1/20 0.48
CHRM1 P11229 1/20 0.47
TTR P02766 3/20 0.46
MRGPRX4 Q96LA9 3/20 0.45
ALDH1A1 P00352 2/20 0.44
GAA P10253 2/20 0.44
HPGD P15428 2/20 0.44
POLB P06746 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP1B1 Q16678 1/20 0.44
DHODH Q02127 1/20 0.44
CYP2C9 P11712 1/20 0.43
FABP3 P05413 3/20 0.43
FABP4 P15090 3/20 0.43
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6532790 0.76 CYP1A2 (0.47) MAPTPLA2G1BATG4BCHRM1TTR
SCHEMBL5823723 0.74 ALDH1A1 (0.50) MAPTALDH1A1GAAHPGDNPC1
SCHEMBL7699106 0.74 DHODH (0.58) ALDH1A1GAAHPGDPOLBL3MBTL1
SCHEMBL10416743 0.73 KMT2A (0.43) MAPTALDH1A1GAAHPGDPOLB
SCHEMBL28797639 0.73 DOT1L (0.46) MAPTALDH1A1GAAHPGDPOLB
SCHEMBL9422350 0.71 NPC1 (0.49) MAPTALDH1A1GAAHPGDPOLB
SCHEMBL10583775 0.71 DHODH (0.69) CYP1A1CYP1A2CYP1B1DHODHCYP2C9
SCHEMBL17941847 0.70 KMT2A (0.57) MAPTCHRM1ALDH1A1GAAHPGD
SCHEMBL641133 0.70 HPGD (0.62) MAPTPLA2G1BATG4BCHRM1TTR
SCHEMBL12471647 0.70 ALDH1A1 (0.45) MAPTALDH1A1GAAHPGDPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050166290-A1 Expression cassettes and methods for delivery of animal vaccines ALL BENJAMIN P (US) 2005-07-28 US disclosed
US-20020058312-A1 Expression cassetts and methods for delivery of animal vaccines APPLIED BIOTECHNOLOGY INSTITUTE LLC 2002-05-16 US disclosed
WO-1997010347-A1 EXPRESSION CASSETTES AND METHODS FOR DELIVERY OF ANIMAL VACCINES HOWARD JOHN A (US) 1997-03-20 WO disclosed