Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | SI | P14410 | 2/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 5/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1480499 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TLR8MGAMGAASI | |
| SCHEMBL1480504 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TLR8MGAMGAASI | |
| SCHEMBL6532905 | 1.00 | ALDH1A1 (0.44) | ALDH1A1TLR8MGAMGAASI | |
| SCHEMBL1481444 | 0.88 | NPC1 (0.43) | ALDH1A1TLR8GAAMAPTKDM4E | |
| SCHEMBL1481442 | 0.88 | NPC1 (0.43) | ALDH1A1TLR8GAAMAPTKDM4E | |
| SCHEMBL1480985 | 0.86 | TLR8 (0.41) | ALDH1A1TLR8MAPTKDM4ECYP1A2 | |
| SCHEMBL1480989 | 0.86 | TLR8 (0.41) | ALDH1A1TLR8MAPTKDM4ECYP1A2 | |
| SCHEMBL1480865 | 0.85 | ERBB2 (0.46) | TLR8 | |
| SCHEMBL6529127 | 0.85 | TLR8 (0.44) | ALDH1A1TLR8MAPTKDM4ECYP1A2 | |
| SCHEMBL1480879 | 0.85 | ERBB2 (0.37) | ALDH1A1TLR8GAAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004071447-A9 | SUBSTITUTED AZOLE DERIVATIVES AS THERAPEUTIC AGENTS | TRANSTECH PHARMA INC (US) | 2005-10-13 | — | — | WO | disclosed |