Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 2/20 | 0.35 |
| ▸ | FYN | P06241 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3134540 | 0.86 | TSHR (0.40) | KDM4EALDH1A1HSD17B10TDP1LMNA | |
| SCHEMBL582872 | 0.84 | ALDH1A1 (0.43) | AURKAAURKBKDM4EALOX12MAOA | |
| SCHEMBL3776131 | 0.83 | CDK2 (0.44) | MAOACDK2ALDH1A1HSD17B10TDP1 | |
| SCHEMBL5432881 | 0.81 | AURKA (0.41) | AURKAAURKBKDM4EALOX12MAOA | |
| SCHEMBL2846139 | 0.80 | DAPK1 (0.37) | KDM4EMAOAALDH1A1HSD17B10TDP1 | |
| SCHEMBL359454 | 0.77 | AURKA (0.47) | AURKAAURKBKDM4EALOX12MAOA | |
| SCHEMBL10797668 | 0.77 | TTR (0.46) | AURKAAURKBALDH1A1HSD17B10TDP1 | |
| SCHEMBL27322855 | 0.77 | TDP1 (0.36) | KDM4EALDH1A1HSD17B10TDP1HPGD | |
| SCHEMBL4163078 | 0.77 | MAOA (0.43) | AURKAAURKBKDM4EALOX12MAOA | |
| Ammonia Solution, Strong SCHEMBL10891448 | 0.76 | AURKA (0.46) | AURKAAURKBKDM4EALOX12MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083937-A1 | RADIOIOINATED PHENOLS FOR BRACHYTHERAPY | THE DOW CHEMICAL COMPANY (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062564-A1 | RADIOIODINATED PHENOLS FOR BRACHYTHERAPY | THE DOW CHEMICAL COMPANY (US) | 1999-12-09 | — | — | WO | disclosed |
| US-798807-A | INDOPHENOL SULFONIC ACIDS AND PROCESS OF MAKING SAME. | OEHLER ANILIN & ANILINFARBEN FABRIK K (DE) | 1905-09-05 | — | — | US | disclosed |