Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15040636 | 0.86 | ALDH1A1 (0.46) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9066792 | 0.82 | KDM4E (0.59) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL729010 | 0.77 | IDO1 (0.55) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL32575454 | 0.77 | IDO1 (0.55) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL31191252 | 0.77 | ALDH1A1 (0.54) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL2962223 | 0.76 | TDP1 (0.57) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL9162775 | 0.75 | IDO1 (0.63) | TDP1IDO1ALDH1A1HSD17B10TSHR | |
| SCHEMBL11806943 | 0.75 | TDP1 (0.44) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL21247464 | 0.73 | TDP1 (0.42) | TDP1IDO1ALDH1A1HSD17B10HPGD | |
| SCHEMBL2514448 | 0.72 | ALDH1A1 (0.45) | TDP1ALDH1A1HSD17B10HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030782-A2 | CARBENE LIGANDS AND THEIR USE | UNIVERSITY OF OTTAWA (CA) | 2005-04-07 | — | — | WO | disclosed |