Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17716009 | 0.89 | TDP1 (0.48) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL30461968 | 0.84 | MAPT (0.50) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL10674706 | 0.84 | MDM4 (0.50) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL4750832 | 0.84 | MAPT (0.50) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL775014 | 0.83 | ALDH1A1 (0.63) | TDP1LMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL22661279 | 0.83 | TDP1 (0.43) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL29379826 | 0.83 | ALDH1A1 (0.63) | TDP1LMNAALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL104062 | 0.82 | IDO1 (0.59) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL632301 | 0.82 | L3MBTL1 (0.49) | TDP1IDO1LMNAALDH1A1L3MBTL1 | |
| SCHEMBL3228979 | 0.82 | TDP1 (0.46) | TDP1IDO1LMNAALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567481-A1 | METHOD FOR INHIBITING POLYMERIZATION DURING THE RECOVERY AND PURIFICATION OF UNSATURATED MONONITRILES | The Standard Oil Company (US) | 2005-08-31 | — | — | EP | claimed |
| WO-2004052842-A1 | METHOD FOR INHIBITING POLYMERIZATION DURING THE RECOVERY AND PURIFICATION OF UNSATURATED MONONITRILES | THE STANDARD OIL COMPANY (US) | 2004-06-24 | — | — | WO | claimed |
| US-8212078-B2 | Making chain extenders with slower cure rates; reacting a ketone and/or aldehyde with a primary amine in the presence of an acidic ion exchange resin and hydrogenation agent; making diimine same way but excluding hydrogenation agent; e.g. N,N'-di-5-nonyl-isophoronediamine | ALBEMARLE CORPORATION (US) | 2012-07-03 | — | — | US | disclosed |
| WO-2010101560-A1 | BIS[(ALKYLAMINO)ALKYL]AMINES | ALBEMARLE CORPORATION (US) | 2010-09-10 | — | — | WO | disclosed |
| US-7767858-B2 | Diimines and secondary diamines | ALBEMARLE CORPORATION (US) | 2010-08-03 | — | — | US | disclosed |
| EP-2143707-A2 | Secondary diamine | Albermarle Corporation (US) | 2010-01-13 | — | — | EP | disclosed |
| US-20080315155-A1 | Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-12-25 | — | — | US | disclosed |
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | ALBEMARLE CORPORATION (US) | 2008-10-23 | — | — | US | disclosed |
| EP-1966122-A1 | DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1966265-A2 | BLENDS OF DIAMINES HAVING REDUCED COLOR | Albermarle Corporation (US) | 2008-09-10 | — | — | EP | disclosed |
| US-20080194788-A1 | Diimines and Secondary Diamines | ALBEMARLE CORPORATION (US) | 2008-08-14 | — | — | US | disclosed |
| US-6410490-B1 | OIL ADDITIVE MIXTURE | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-25 | — | — | US | disclosed |
| US-4486603-A | Preparation of trans cyclohexane 1,4-diamine | AKZONA INCORPORATED (US) | 1984-12-04 | — | — | US | disclosed |
| US-4467114-A | Preparation of trans cyclohexane 1,4-diurea | AKZONA INCORPORATED (US) | 1984-08-21 | — | — | US | disclosed |
| US-4457871-A | Preparation of trans cyclohexane,1,4-diisocyanate and related compounds | AKZONA INCORPORATED (US) | 1984-07-03 | — | — | US | disclosed |
| US-4439370-A | Preparation of trans cyclohexane 1,4-diisocyanate | AKZONA INCORPORATED (US) | 1984-03-27 | — | — | US | disclosed |
| US-4418211-A | Preparation of trans-cyclohexane-1,4-disulphonyl urea | AKZONA INCORPORATED (US) | 1983-11-29 | — | — | US | disclosed |
| US-4275223-A | Preparation of trans-cyclohexane-1,4-diurethanes | AKZONA INCORPORATED (US) | 1981-06-23 | — | — | US | disclosed |
| US-4203916-A | Preparation of trans cyclohexane 1,4 diisocyanate | AKZONA INCORPORATED (US) | 1980-05-20 | — | — | US | disclosed |
| US-4140718-A | Preparation of N,N'-dialkylphenylenediamines | UOP INC. (US) | 1979-02-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262187-A1 | Blends of Diamines Having Reduced Color | DDT, DDC, AOC1 | TDP1 483/4885IDO1 77/4885LMNA 155/4885 |
| US-20080315155-A1 | Diamines Having Reduced Color | DDT, DPYD, DDC | TDP1 486/4885IDO1 479/4885LMNA 635/4885 |
| US-20080194788-A1 | Diimines and Secondary Diamines | DDT, DDC, AOC1 | TDP1 1248/4885IDO1 6/4885LMNA 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.