Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.38 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15302506 | 0.92 | — | — | |
| SCHEMBL720694 | 0.81 | — | — | |
| SCHEMBL29179306 | 0.75 | TSHR (0.39) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL3124748 | 0.74 | TSHR (0.48) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL20537287 | 0.74 | TSHR (0.42) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL2585548 | 0.74 | TSHR (0.48) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL1330037 | 0.72 | TSHR (0.46) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL1331301 | 0.72 | TSHR (0.46) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL4528774 | 0.72 | TSHR (0.46) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH | |
| SCHEMBL8057774 | 0.72 | TSHR (0.46) | TSHRZDHHC20ZDHHC2ALDH1A1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188763-B1 | Metallocenes and their use in olefin polymerisation | BASELL POLYOLEFINE GMBH (DE) | 2005-03-09 | — | — | EP | claimed |
| WO-2016024074-A1 | POLY(CARBORANE-CO-SILOXANES) AND METHODS FOR THEIR PRODUCTION | THE SECRETARY OF STATE FOR DEFENCE (GB) | 2016-02-18 | — | — | WO | disclosed |
| US-5741868-A | Olefin polymerization process by using a substituted indenyl containing metallocene catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-04-21 | — | — | US | disclosed |
| US-5612428-A | CATALYTIC POLYMERIZATION WITH COORDINATION COMPLEXES WITH GROUP IVB METALS AND COCATALYSTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| US-5576260-A | POLYMERIZATION CATALYSTS FOR OLEFINS | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-19 | — | — | US | disclosed |
| US-5543373-A | OLEFIN POLYMERIZATION CATALYST | HOECHST AG (DE) | 1996-08-06 | — | — | US | disclosed |
| US-5532396-A | HAS TWO INDENYL LIGANDS WITH DIFFERENT SUBSTITUTION PATTERNS ON THE SIX-MEMBERED RINGS. LIGANDS ARE JOINED BY DIVALENT GROUP CONNECTING FIVE-MEMBERED RINGS. METAL IS FROM GROUP /IVB/, /VB/ OR /VIB/. OLEFIN POLYMERIZATION CATALYST | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |