Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10898385 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1331470 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL29156489 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1330037 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL29156630 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL30728575 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1330559 | 1.00 | TSHR (0.46) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL20537287 | 0.97 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1474752 | 0.89 | TSHR (0.41) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL3124748 | 0.81 | TSHR (0.48) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10093757-B2 | Silanol condensation catalysts for the cross-linking of filled and unfilled polymer compounds | EVONIK DEGUSSA GMBH (DE) | 2018-10-09 | — | — | US | disclosed |
| US-20130253144-A1 | SILANOL CONDENSATION CATALYSTS FOR THE CROSS-LINKING OF FILLED AND UNFILLED POLYMER COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2013-09-26 | — | — | US | disclosed |
| EP-2465897-B1 | Master kit containing silanol condensation catalysts for integrating filled and unfilled polymer compounds | EVONIK DEGUSSA GMBH (DE) | 2012-12-26 | — | — | EP | disclosed |
| EP-2465897-A1 | Master kit containing silanol condensation catalysts for integrating filled and unfilled polymer compounds | Evonik Degussa GmbH (DE) | 2012-06-20 | — | — | EP | disclosed |
| US-20110282024-A1 | CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES | EVONIK DEGUSSA GMBH (DE) | 2011-11-17 | — | — | US | disclosed |
| US-20110144278-A1 | SILANOL CONDENSATION CATALYSTS FOR THE CROSS-LINKING OF FILLED AND UNFILLED POLYMER COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
| US-20110144277-A1 | USE OF SILICON-CONTAINING PRECURSOR COMPOUNDS OF AN ORGANIC ACID AS A CATALYST FOR CROSS-LINKING FILLED AND UNFILLED POLYMER COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2011-06-16 | — | — | US | disclosed |
| EP-2331622-A1 | NEW CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES | Evonik Degussa GmbH (DE) | 2011-06-15 | — | — | EP | disclosed |
| WO-2010028877-A1 | NEW CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES | EVONIK DEGUSSA GMBH (DE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110282024-A1 | CATALYSTS FOR THE CROSS-LINKING OF FUNCTIONAL SILANES OR FUNCTIONAL SILOXANES, PARTICULARLY WITH SUBSTRATES | SI, FOXO1, F11 | TSHR 3535/4885THRB 4135/4885ZDHHC20 1211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.