Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | BCR | P11274 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1369320 | 0.86 | HSD17B1 (0.50) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL148071 | 0.86 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL2446899 | 0.86 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL1371905 | 0.85 | HSD17B1 (0.44) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL28586676 | 0.85 | ESR1 (0.52) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL2271000 | 0.84 | ESR1 (0.50) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL2453077 | 0.83 | ESR1 (0.48) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL2447055 | 0.83 | ESR1 (0.48) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL1002340 | 0.82 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2CYP1A2 | |
| SCHEMBL2448124 | 0.80 | ESR1 (0.47) | ESR1ESR2HSD17B1HSD17B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110063552-A1 | LIQUID CRYSTAL DISPLAY DEVICE, AND LIQUID CRYSTAL CELL | FUJIFILM CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
| US-6166168-A | Application of sulfone, ketone and ester containing polyalkyl ether units to medical materials | TEIJIN LIMITED (JP) | 2000-12-26 | — | — | US | disclosed |
| US-5969082-A | FOR MEMBRANES, TUBES, HOLLOW YARNS, CONTAINERS, SUTURES WHICH COME IN CONTACT WITH BLOOD | TEIJIN LIMITED (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0781795-A2 | Application of sulfone, ketone and ester containing polyalkyl ethers to medical materials | TEIJIN LIMITED (JP) | 1997-07-02 | — | — | EP | disclosed |