Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2446899 | 1.00 | ESR1 (0.52) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2447055 | 0.96 | ESR1 (0.48) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2453077 | 0.96 | ESR1 (0.48) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2251915 | 0.92 | ESR1 (0.48) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2256257 | 0.92 | ESR1 (0.48) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2256245 | 0.92 | ESR1 (0.50) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL2271000 | 0.90 | ESR1 (0.50) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL1002340 | 0.88 | ESR1 (0.40) | ESR1ESR2HSD17B1HSD17B2CYP11B1 | |
| SCHEMBL2452660 | 0.87 | GSTP1 (0.40) | ESR1ESR2BACE1HSD17B1HSD17B2 | |
| SCHEMBL6533069 | 0.86 | ESR1 (0.37) | ESR1ESR2BACE1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230337532-A1 | TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | TOSOH CORPORATION (JP) | 2023-10-19 | — | — | US | claimed |
| CN-116348454-A | Triazine compound, material for organic electroluminescent element, electron-transporting material for organic electroluminescent element, and organic electroluminescent element | 东曹株式会社 | 2023-06-27 | — | — | CN | claimed |
| WO-2022075219-A1 | TRIAZINE COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ELECTRON TRANSPORT MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT | 東ソー株式会社 | 2022-04-14 | — | — | WO | claimed |
| CN-106632392-A | Benzothieno carbazole type organic luminescent material, preparation method thereof and organic luminescent device | 上海升翕光电科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106632413-A | Benzothiophene carbazole type derivative, preparation method of benzothiophene carbazole type derivative and organic luminous device | 上海升翕光电科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| US-9024304-B2 | Naphthalene derivative, organic material including the same, and organic electroluminescent device including the same | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2015-05-05 | — | — | US | claimed |
| EP-2611774-B1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2015-03-18 | — | — | EP | claimed |
| US-20140299849-A1 | NAPHTHALENE DERIVATIVE, ORGANIC MATERIAL INCLUDING THE SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE INCLUDING THE SAME | DAE JOO ELECTRONIC MATERIALS CO., LTD. (KR) | 2014-10-09 | — | — | US | claimed |
| US-8759533-B2 | Di-azetidinyl diamide as monoacylglcerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2014-06-24 | — | — | US | claimed |
| EP-2692823-A2 | NAPHTHALENE DERIVATIVES, ORGANIC MATERIAL USING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | Dae Joo Electronic Materials Co., Ltd. (KR) | 2014-02-05 | — | — | EP | claimed |
| CN-103534331-A | Naphthalene derivatives, organic material using same, and organic electroluminescent device using same | DAE JOO ELECTRONIC MAT CO LTD | 2014-01-22 | — | — | CN | claimed |
| US-20130196968-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA, NV (BE) | 2013-08-01 | — | — | US | claimed |
| EP-2611774-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica, N.V. (BE) | 2013-07-10 | — | — | EP | claimed |
| US-8362001-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2013-01-29 | — | — | US | claimed |
| WO-2012030907-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2012-03-08 | — | — | WO | claimed |
| US-20120058986-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2012-03-08 | — | — | US | claimed |
| EP-2421848-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | Janssen Pharmaceutica N.V. (BE) | 2012-02-29 | — | — | EP | claimed |
| US-20100331300-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-30 | — | — | US | claimed |
| WO-2010124119-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-10-28 | — | — | WO | claimed |
| US-7560604-B2 | Biphenyl derivative, material for organic electroluminescence device, and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2009-07-14 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130196968-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLCEROL LIPASE INHIBITORS | MGLL, PNLIP, LPL | ESR1 4568/4885ESR2 4135/4885BACE1 2756/4885 |
| US-20120058986-A1 | DI-AZETIDINYL DIAMIDE AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | ESR1 4234/4885ESR2 3448/4885BACE1 2398/4885 |
| US-20230337532-A1 | TRIAZINE COMPOUND, MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, ELECTRON TRANSPORT MATERIAL FOR ORGANIC LIGHT EMITTING DIODE, AND ORGANIC LIGHT EMITTING DIODE | ARNT, TPH1, AHR | ESR1 423/4885ESR2 174/4885BACE1 2851/4885 |
| US-20100331300-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | ESR1 2868/4885ESR2 2261/4885BACE1 1751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.