Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4836350 | 0.86 | CYP2C9 (0.46) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4826152 | 0.82 | MAPT (0.51) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL27613226 | 0.82 | MAPT (0.59) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL6432318 | 0.80 | GAA (0.49) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4826040 | 0.80 | NPC1 (0.44) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4831316 | 0.78 | ALDH1A1 (0.49) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL27612962 | 0.78 | MAPT (0.43) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4828997 | 0.77 | ENPP2 (0.44) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4834860 | 0.76 | MAPT (0.44) | HCAR2CYP2C8CYP2C9NPC1RAB9A | |
| SCHEMBL4834870 | 0.75 | ALDH1A1 (0.43) | HCAR2CYP2C8CYP2C9NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1556032-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | Takeda Pharmaceutical Company Limited (JP) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004039365-A1 | AGENT FOR PREVENTING OR TREATING NEUROPATHY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-05-13 | — | — | WO | disclosed |