Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 8/20 | 0.34 |
| ▸ | PPARA | Q07869 | 8/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533825 | 0.94 | PPARG (0.37) | ROCK2PPARGPPARAAKT1 | |
| SCHEMBL6532874 | 0.93 | PPARG (0.40) | ROCK2PPARGPPARACNR1 | |
| SCHEMBL6532684 | 0.93 | PPARG (0.38) | ROCK2PPARGPPARA | |
| SCHEMBL6533025 | 0.93 | PPARG (0.40) | PPARGPPARAMAOB | |
| SCHEMBL6532383 | 0.92 | PPARG (0.40) | ROCK2PPARGPPARA | |
| SCHEMBL6533886 | 0.89 | PPARG (0.36) | PPARGPPARA | |
| SCHEMBL6532334 | 0.88 | PPARG (0.35) | PTGS2PPARGPPARA | |
| SCHEMBL6532514 | 0.87 | CXCR1 (0.34) | PTGS2PPARGPPARA | |
| SCHEMBL6534035 | 0.87 | ACACB (0.38) | ROCK2PPARGPPARAMAOB | |
| SCHEMBL6533725 | 0.87 | PPARG (0.42) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |