Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 6/20 | 0.37 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARA | Q07869 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532383 | 0.92 | PPARG (0.40) | ACACBPPARGPPARAROCK2ROCK1 | |
| SCHEMBL6532684 | 0.91 | PPARG (0.38) | ACACBPPARGPPARAROCK2ROCK1 | |
| SCHEMBL6532243 | 0.89 | MME (0.36) | MAOBPPARGPPARAROCK2ROCK1 | |
| SCHEMBL6533257 | 0.87 | ROCK2 (0.34) | MAOBPPARGPPARAROCK2 | |
| SCHEMBL6532334 | 0.85 | PPARG (0.35) | ACACBPPARGPPARA | |
| SCHEMBL6532874 | 0.85 | PPARG (0.40) | ACACBPPARGPPARAROCK2ROCK1 | |
| SCHEMBL6532377 | 0.84 | PPARG (0.39) | PPARGPPARAROCK2ROCK1 | |
| SCHEMBL6532102 | 0.84 | PPARG (0.39) | PPARGPPARAROCK2ROCK1 | |
| SCHEMBL6532609 | 0.84 | PPARG (0.47) | PPARGPPARA | |
| SCHEMBL6533886 | 0.84 | PPARG (0.36) | ACACBPPARGPPARAROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |