Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.36 |
| ▸ | PPARA | Q07869 | 14/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | MYLK4 | Q86YV6 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532377 | 0.97 | PPARG (0.39) | PPARGPPARAPPARDATML3MBTL1 | |
| SCHEMBL6534151 | 0.92 | PPARG (0.42) | PPARGPPARA | |
| SCHEMBL6532684 | 0.90 | PPARG (0.38) | PPARGPPARAPPARDROCK1ACACB | |
| SCHEMBL6532102 | 0.90 | PPARG (0.39) | PPARGPPARAPPARDL3MBTL1ROCK1 | |
| SCHEMBL6533744 | 0.90 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL6533825 | 0.89 | PPARG (0.37) | PPARGPPARAPPARD | |
| SCHEMBL6532383 | 0.89 | PPARG (0.40) | PPARGPPARAROCK1ACACB | |
| SCHEMBL6533257 | 0.89 | ROCK2 (0.34) | PPARGPPARA | |
| SCHEMBL6532874 | 0.88 | PPARG (0.40) | PPARGPPARAROCK1ACACB | |
| SCHEMBL6532809 | 0.88 | PPARG (0.49) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |