Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.38 |
| ▸ | PPARG | P37231 | 15/20 | 0.38 |
| ▸ | GRK6 | P43250 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534136 | 0.95 | PPARA (0.39) | PPARAPPARGMMEACECPA1 | |
| SCHEMBL6534060 | 0.93 | PPARG (0.44) | PPARAPPARG | |
| SCHEMBL6532153 | 0.88 | PPARG (0.45) | PPARAPPARG | |
| SCHEMBL6532383 | 0.82 | PPARG (0.40) | PPARAPPARG | |
| SCHEMBL6532543 | 0.79 | PPARG (0.52) | PPARAPPARGGPR34 | |
| SCHEMBL6531718 | 0.77 | PPARG (0.39) | PPARAPPARG | |
| SCHEMBL6534035 | 0.76 | ACACB (0.38) | PPARAPPARG | |
| SCHEMBL6532243 | 0.76 | MME (0.36) | PPARAPPARGMMEACECPA1 | |
| SCHEMBL6532874 | 0.75 | PPARG (0.40) | PPARAPPARG | |
| SCHEMBL6532684 | 0.75 | PPARG (0.38) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |