Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.39 |
| ▸ | PPARA | Q07869 | 13/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 2/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532383 | 0.81 | PPARG (0.40) | PPARGPPARAACACBMMP1MMP2 | |
| SCHEMBL6532874 | 0.81 | PPARG (0.40) | PPARGPPARAACACBNOS2MMP1 | |
| SCHEMBL6532486 | 0.80 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL6533291 | 0.77 | PPARA (0.38) | PPARGPPARA | |
| SCHEMBL6534136 | 0.76 | PPARA (0.39) | PPARGPPARA | |
| SCHEMBL6533257 | 0.75 | ROCK2 (0.34) | PPARGPPARA | |
| SCHEMBL6533886 | 0.75 | PPARG (0.36) | PPARGPPARAACACB | |
| SCHEMBL6532684 | 0.74 | PPARG (0.38) | PPARGPPARAACACB | |
| SCHEMBL6532609 | 0.74 | PPARG (0.47) | PPARGPPARAMMP1MMP2MMP9 | |
| SCHEMBL6531716 | 0.74 | PPARG (0.41) | PPARGPPARAFFAR1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |