SCHEMBL6533418

SCHEMBL6533418

CC(N)(C(=O)O)C(Cl)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.44
CYP2D6 P10635 2/20 0.43
CYP1A2 P05177 1/20 0.43
SRC P12931 1/20 0.39
MAPT P10636 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HSP90AA1 P07900 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
KMT2A Q03164 1/20 0.38
TSHR P16473 1/20 0.38
ALOX5 P09917 1/20 0.38
AOC3 Q16853 1/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 1/20 0.38
GRM2 Q14416 2/20 0.37
GRM3 Q14832 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HIF1A Q16665 1/20 0.37
CTSD P07339 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6438147 0.81 CYP2C19 (0.44) CYP2C19CYP2D6CYP1A2SRCMAPT
SCHEMBL4551688 0.79 CYP2D6 (0.41) CYP2C19CYP2D6CYP1A2L3MBTL1AOC3
SCHEMBL29141154 0.78 CYP1A2 (0.42) CYP2C19CYP2D6CYP1A2SRCTSHR
SCHEMBL10690917 0.78 CYP1A2 (0.42) CYP2C19CYP2D6CYP1A2SRCMAPT
SCHEMBL8496310 0.78 CYP2D6 (0.48) CYP2C19CYP2D6CYP1A2SRCMAPT
SCHEMBL3109355 0.78 AOC3 (0.52) CYP2C19CYP2D6CYP1A2SRCL3MBTL1
SCHEMBL3109358 0.78 AOC3 (0.52) CYP2C19CYP2D6CYP1A2SRCL3MBTL1
SCHEMBL5940495 0.78 CYP2D6 (0.48) CYP2C19CYP2D6CYP1A2SRCMAPT
SCHEMBL27289370 0.77 TSHR (0.46) TSHRAOC3LMNAHIF1A
Hydrochloric Acid SCHEMBL1311457 0.77 CYP2D6 (0.47) CYP2C19CYP2D6CYP1A2SRCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005030735-A1 TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (IN) 2005-04-07 WO claimed