Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22074702 | 0.85 | BLM (0.46) | CYP2C19SRCLMNA | |
| SCHEMBL25596204 | 0.85 | ALDH1A1 (0.42) | CYP2C19ATMLMNAKMT2AHTT | |
| SCHEMBL6533418 | 0.81 | CYP2C19 (0.44) | CYP2C19CYP1A2CYP2D6SRCATM | |
| SCHEMBL6533964 | 0.79 | GAA (0.43) | CYP2C19CYP1A2CYP2D6KMT2A | |
| SCHEMBL23723006 | 0.78 | CYP2D6 (0.40) | CYP2C19CYP1A2CYP2D6SRCLMNA | |
| SCHEMBL5940495 | 0.78 | CYP2D6 (0.48) | CYP2C19CYP1A2CYP2D6SRCATM | |
| SCHEMBL3109358 | 0.78 | AOC3 (0.52) | CYP2C19CYP1A2CYP2D6SRCL3MBTL1 | |
| SCHEMBL8496310 | 0.78 | CYP2D6 (0.48) | CYP2C19CYP1A2CYP2D6SRCATM | |
| SCHEMBL3109355 | 0.78 | AOC3 (0.52) | CYP2C19CYP1A2CYP2D6SRCL3MBTL1 | |
| SCHEMBL21243976 | 0.78 | SLC6A4 (0.41) | LMNARIPK1AOC3SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005030735-A1 | TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | claimed |
| US-20150045328-A1 | DISUBSTITUTED ARYL OXY DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | ALLERGAN, INC. | 2015-02-12 | — | — | US | disclosed |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045328-A1 | DISUBSTITUTED ARYL OXY DERIVATIVES AS SPHINGOSINE-1 PHOSPHATE RECEPTORS MODULATORS | S1PR1, S1PR3, S1PR2 | CYP2C19 2679/4885CYP1A2 1998/4885CYP2D6 1447/4885 |
| US-20050256160-A1 | Beta-alanine derivatives and the use thereof | TGFB1, PML, APOB | CYP2C19 3960/4885CYP1A2 2649/4885CYP2D6 3477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.