Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 11/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531126 | 0.88 | TMEM97 (0.50) | TMEM97LMNAALDH1A1 | |
| SCHEMBL6533465 | 0.86 | TMEM97 (0.45) | TMEM97LMNAALDH1A1 | |
| SCHEMBL6531544 | 0.84 | TMEM97 (0.43) | TMEM97 | |
| SCHEMBL6479225 | 0.80 | PRMT5 (0.41) | TMEM97LMNARAB9AALDH1A1 | |
| SCHEMBL2803707 | 0.74 | TMEM97 (0.55) | TMEM97POLBATMRAB9AALDH1A1 | |
| SCHEMBL13016805 | 0.73 | TMEM97 (0.48) | TMEM97LMNAATMRAB9AALDH1A1 | |
| SCHEMBL3122259 | 0.73 | TMEM97 (0.48) | TMEM97LMNAATMRAB9AALDH1A1 | |
| SCHEMBL3112716 | 0.73 | TMEM97 (0.50) | TMEM97LMNARAB9AALDH1A1 | |
| SCHEMBL220610 | 0.71 | TMEM97 (0.57) | TMEM97RAB9AMRGPRX4 | |
| SCHEMBL5520643 | 0.71 | POLB (0.57) | POLBLMNAATMRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572627-A1 | DRUGS FOR CHRONIC PAIN | Nicox S.A. (FR) | 2005-09-14 | — | — | EP | claimed |
| WO-2004054965-A1 | DRUGS FOR CHRONIC PAIN | NICOX S.A. (FR) | 2004-07-01 | — | — | WO | claimed |
| EP-1572627-A1 | DRUGS FOR CHRONIC PAIN | Nicox S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054965-A1 | DRUGS FOR CHRONIC PAIN | NICOX S.A. (FR) | 2004-07-01 | — | — | WO | disclosed |