Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533444 | 0.86 | TMEM97 (0.55) | TMEM97ALDH1A1LMNA | |
| SCHEMBL6531544 | 0.83 | TMEM97 (0.43) | TMEM97 | |
| SCHEMBL6531412 | 0.82 | ALDH1A1 (0.35) | TMEM97ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27632659 | 0.79 | TMEM97 (0.39) | TMEM97ALDH1A1ROCK2ROCK1LMNA | |
| SCHEMBL6478425 | 0.79 | CYP2C9 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL3119889 | 0.77 | TMEM97 (0.41) | TMEM97ALDH1A1ROCK2ROCK1LMNA | |
| SCHEMBL13016818 | 0.77 | TMEM97 (0.39) | TMEM97ALDH1A1ROCK2ROCK1 | |
| SCHEMBL3104786 | 0.77 | TMEM97 (0.39) | TMEM97ALDH1A1ROCK2ROCK1 | |
| SCHEMBL6531126 | 0.76 | TMEM97 (0.50) | TMEM97ALDH1A1LMNA | |
| SCHEMBL6479225 | 0.71 | PRMT5 (0.41) | TMEM97ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572627-A1 | DRUGS FOR CHRONIC PAIN | Nicox S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054965-A1 | DRUGS FOR CHRONIC PAIN | NICOX S.A. (FR) | 2004-07-01 | — | — | WO | disclosed |