Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6531412 | 0.86 | ALDH1A1 (0.35) | MEN1KMT2AKDM4EALDH1A1TMEM97 | |
| SCHEMBL6531126 | 0.81 | TMEM97 (0.50) | ALDH1A1TMEM97MAPTLMNAHTT | |
| SCHEMBL6533444 | 0.80 | TMEM97 (0.55) | ALDH1A1TMEM97LMNARAB9A | |
| SCHEMBL6531544 | 0.74 | TMEM97 (0.43) | TMEM97 | |
| SCHEMBL6478425 | 0.72 | CYP2C9 (0.33) | MEN1KMT2AALDH1A1CYP2C19 | |
| SCHEMBL13016806 | 0.72 | EGLN2 (0.42) | PRMT5KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3111586 | 0.72 | EGLN2 (0.42) | PRMT5KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL3117385 | 0.72 | LMNA (0.44) | MEN1KMT2AALDH1A1EGLN2EGLN1 | |
| SCHEMBL6533465 | 0.71 | TMEM97 (0.45) | MEN1KMT2AALDH1A1TMEM97LMNA | |
| SCHEMBL2960866 | 0.70 | TP53 (0.50) | MEN1KMT2AKDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572627-A1 | DRUGS FOR CHRONIC PAIN | Nicox S.A. (FR) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004054965-A1 | DRUGS FOR CHRONIC PAIN | NICOX S.A. (FR) | 2004-07-01 | — | — | WO | disclosed |