Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6532738 | 0.90 | MEN1 (0.52) | MEN1KMT2AFFAR4FFAR1LMNA | |
| SCHEMBL6516529 | 0.88 | MEN1 (0.59) | MEN1KMT2AFFAR4FFAR1CETP | |
| SCHEMBL6510100 | 0.84 | FFAR1 (0.41) | FFAR4FFAR1SLC1A5MAPT | |
| SCHEMBL6513398 | 0.84 | KMT2A (0.44) | MEN1KMT2AFFAR4FFAR1LMNA | |
| SCHEMBL6510780 | 0.82 | TSHR (0.49) | FFAR4FFAR1PTGESTDP1MAPT | |
| SCHEMBL6510314 | 0.81 | HPGD (0.40) | FFAR4FFAR1HPGDSLC1A5PTGES | |
| SCHEMBL6511174 | 0.81 | FFAR1 (0.43) | FFAR4FFAR1MAPT | |
| SCHEMBL6511699 | 0.80 | FFAR1 (0.43) | FFAR4FFAR1THRBGAAMAPT | |
| SCHEMBL6510695 | 0.80 | FFAR1 (0.43) | MEN1KMT2AFFAR4FFAR1SLC1A5 | |
| SCHEMBL6511036 | 0.79 | PPARA (0.42) | FFAR4FFAR1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |