Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511036 | 0.99 | PPARA (0.42) | FFAR1FFAR4PPARAPPARGNPC1 | |
| SCHEMBL6511174 | 0.97 | FFAR1 (0.43) | FFAR1FFAR4PPARAPPARGNPC1 | |
| SCHEMBL6510672 | 0.90 | RAB9A (0.42) | PPARAPPARGRAB9AS1PR1PLK1 | |
| SCHEMBL6531857 | 0.89 | PPARA (0.42) | PPARAPPARGRAB9AS1PR1THRB | |
| SCHEMBL6509250 | 0.88 | CSF1R (0.39) | FFAR4PPARAPPARGNPC1RAB9A | |
| SCHEMBL6509334 | 0.88 | PPARA (0.46) | FFAR4PPARAPPARGNPC1RAB9A | |
| SCHEMBL6509333 | 0.87 | FFAR1 (0.46) | FFAR1FFAR4PPARGNPC1RAB9A | |
| SCHEMBL6510841 | 0.87 | PPARA (0.48) | PPARAPPARGS1PR1THRB | |
| SCHEMBL6510860 | 0.86 | RAB9A (0.41) | FFAR1FFAR4PPARAPPARGNPC1 | |
| SCHEMBL6510695 | 0.85 | FFAR1 (0.43) | FFAR1FFAR4MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097100-A2 | ANTIBACTERIAL AGENTS | PROLYSIS LTD. (GB) | 2005-10-20 | — | — | WO | disclosed |