Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.30 |
| ▸ | CMA1 | P23946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508516 | 0.81 | PPARA (0.37) | — | |
| SCHEMBL7202384 | 0.80 | ELANE (0.44) | ELANE | |
| SCHEMBL6502073 | 0.78 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL6533915 | 0.78 | HRH3 (0.33) | KCNN4ELANENPSR1DYRK1ACYP2C19 | |
| SCHEMBL6709910 | 0.77 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL6502656 | 0.74 | CYP4F2 (0.33) | DGAT1 | |
| SCHEMBL6899108 | 0.72 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL11058721 | 0.71 | KCNN4 (0.39) | KCNN4ELANENPSR1CYP2C19ALDH1A1 | |
| SCHEMBL2022397 | 0.71 | DGAT1 (0.44) | KCNN4ELANEDYRK1AALDH1A1SRC | |
| SCHEMBL6505133 | 0.70 | CYP4F2 (0.36) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005047236-A1 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS, INC. (US) | 2005-05-26 | — | — | WO | disclosed |