Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 16/20 | 0.43 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506438 | 0.80 | MAPK14 (0.52) | MAPK14PTGER1 | |
| SCHEMBL6474630 | 0.76 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL6471313 | 0.67 | MAPK14 (0.38) | MAPK14PTGER1PKM | |
| SCHEMBL6533878 | 0.66 | MAPK14 (0.43) | MAPK14MAPKAPK2 | |
| SCHEMBL8999096 | 0.65 | TRIM24 (0.49) | PKM | |
| SCHEMBL4475391 | 0.65 | MAPK14 (0.49) | MAPK14MAPKAPK2 | |
| SCHEMBL4477527 | 0.64 | MAPK14 (0.46) | MAPK14MAPKAPK2 | |
| SCHEMBL6471669 | 0.64 | MAPK14 (0.52) | MAPK14 | |
| SCHEMBL4375353 | 0.64 | MAPK14 (0.60) | MAPK14 | |
| SCHEMBL5861917 | 0.63 | MAPK14 (0.48) | MAPK14MAPKAPK2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005018557-A2 | SUBSTITUTED PYRIDINONES | PHARMACIA CORPORATION (US) | 2005-03-03 | — | — | WO | claimed |