Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.39 |
| ▸ | PPARA | Q07869 | 10/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6533887 | 1.00 | PPARG (0.39) | PPARGPPARAMAOBATMALKBH1 | |
| SCHEMBL6532376 | 0.97 | LTA4H (0.43) | PPARGPPARAATMALKBH1LTA4H | |
| SCHEMBL6532379 | 0.97 | LTA4H (0.43) | PPARGPPARAATMALKBH1LTA4H | |
| SCHEMBL6534150 | 0.92 | PPARG (0.47) | PPARGPPARAMAOB | |
| SCHEMBL6534152 | 0.92 | PPARG (0.47) | PPARGPPARAMAOB | |
| SCHEMBL6532104 | 0.90 | LTA4H (0.43) | PPARGPPARAATMLTA4HNPC1 | |
| SCHEMBL6532687 | 0.90 | LTA4H (0.43) | PPARGPPARAATMLTA4HNPC1 | |
| SCHEMBL6532682 | 0.90 | LTA4H (0.43) | PPARGPPARAATMLTA4HNPC1 | |
| SCHEMBL6532098 | 0.90 | LTA4H (0.43) | PPARGPPARAATMLTA4HNPC1 | |
| SCHEMBL6533743 | 0.90 | PPARG (0.48) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |