Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21753734 | 0.76 | ALDH1A1 (0.50) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL1741077 | 0.72 | ALDH1A1 (0.31) | ALDH1A1TDP1CYP3A4TSHR | |
| SCHEMBL12986142 | 0.71 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL11422088 | 0.70 | — | — | |
| SCHEMBL12976025 | 0.70 | ALDH1A1 (0.46) | ALDH1A1KDM4ELMNAGAAMAPT | |
| SCHEMBL28354051 | 0.68 | — | — | |
| Ammonia Solution, Strong SCHEMBL19260522 | 0.68 | — | — | |
| SCHEMBL14307034 | 0.67 | ERN1 (0.38) | ALDH1A1TDP1TP53TSHR | |
| SCHEMBL8523627 | 0.67 | TDP1 (0.43) | ALDH1A1LMNAMAPTSLC6A2TDP1 | |
| SCHEMBL10292272 | 0.66 | SLC6A2 (0.42) | ALDH1A1KDM4ELMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005056623-A1 | DENTAL COMPOSITIONS CONTAINING LIQUIDS AND OTHER ELASTOMERS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-06-23 | — | — | WO | disclosed |