Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865964 | 0.81 | THRB (0.34) | TDP1ALOX15CYP3A4THRBALDH1A1 | |
| SCHEMBL6684924 | 0.81 | THRB (0.34) | TDP1ALOX15CYP3A4THRBALDH1A1 | |
| SCHEMBL13967832 | 0.79 | TP53 (0.35) | TDP1TP53CYP3A4ALDH1A1MAPT | |
| SCHEMBL21230645 | 0.78 | ALOX15 (0.52) | TDP1ALOX15SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL8238644 | 0.76 | TDP1 (0.50) | TDP1ALOX15SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL1197991 | 0.76 | ALOX15 (0.50) | TDP1ALOX15SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL646259 | 0.72 | CYP3A4 (0.38) | TDP1ALOX15SMN1; SMN2CYP3A4ALDH1A1 | |
| SCHEMBL8238576 | 0.72 | ALOX15 (0.45) | TDP1ALOX15SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL5566753 | 0.72 | ALOX15 (0.45) | TDP1ALOX15SMN1; SMN2TP53CYP3A4 | |
| SCHEMBL13657379 | 0.71 | TSHR (0.51) | TDP1CYP3A4ALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101868218-A | Curable composition for dental applications | TOKUYAMA DENTAL CORP | 2010-10-20 | — | — | CN | disclosed |
| EP-0889933-A1 | METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS | First Chemical Corporation (US) | 1999-01-13 | — | — | EP | disclosed |
| WO-1997035916-A1 | METHODS OF CURING UNSATURATED POLYMERS USING TERTIARY AROMATIC AMINE CURE PROMOTERS | FIRST CHEMICAL CORPORATION (US) | 1997-10-02 | — | — | WO | disclosed |