Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27130162 | 0.86 | HSD17B10 (0.52) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL23803932 | 0.83 | HCAR2 (0.47) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL25329025 | 0.79 | POLB (0.52) | HCAR2RAB9AMAPTALDH1A1CYP1A2 | |
| SCHEMBL21135583 | 0.74 | HCAR2 (0.48) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL27128058 | 0.72 | RAB9A (0.52) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL40333 | 0.72 | — | — | |
| Biphenyl SCHEMBL27870371 | 0.72 | HCAR2 (0.80) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL11864179 | 0.70 | RAB9A (0.50) | ALOX15NPC1RAB9ASMN1; SMN2HPGD | |
| Water SCHEMBL28329906 | 0.70 | HCAR2 (0.53) | HCAR2ALOX15NPC1RAB9ACDK2 | |
| SCHEMBL28285927 | 0.70 | HCAR2 (0.53) | HCAR2ALOX15NPC1RAB9ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6960595-B2 | 5-6 to 5-7 Heterobicycles as factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2005-11-01 | — | — | US | disclosed |
| CN-1445218-A | 3-phenyl pyrazole-5-ramification of carboxylic acid derivative as well as its preparing method and medicine appliction | LIU LIGANG (CN) | 2003-10-01 | — | — | CN | disclosed |
| US-20030018023-A1 | 5-6 or 5-7 Heterobicycles as Factor Xa inhibitors | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018023-A1 | 5-6 or 5-7 Heterobicycles as Factor Xa inhibitors | HABP2, SERPINC1, F7 | HCAR2 4148/4885ALOX15 2068/4885NPC1 3150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.