Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 7/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4206413 | 0.76 | CNR1 (0.39) | CNR1CNR2HSD11B1CYP3A4DPP4 | |
| SCHEMBL6335025 | 0.75 | CNR1 (0.41) | CNR1CNR2 | |
| Lithium Ion SCHEMBL4220249 | 0.74 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL4220252 | 0.74 | CNR1 (0.40) | CNR1CNR2 | |
| SCHEMBL4212958 | 0.72 | CNR1 (0.43) | CNR1CNR2DPP4 | |
| SCHEMBL4215280 | 0.70 | CNR1 (0.56) | CNR1CNR2 | |
| SCHEMBL5008799 | 0.69 | CNR1 (0.35) | CNR1CNR2CYP3A4DPP4DPP8 | |
| SCHEMBL5008797 | 0.69 | CNR1 (0.35) | CNR1CNR2 | |
| SCHEMBL4359770 | 0.68 | CNR1 (0.36) | CNR1CNR2CYP3A4DPP4DPP8 | |
| SCHEMBL13928742 | 0.68 | CNR1 (0.36) | CNR1CNR2CYP3A4DPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005061506-A1 | BICYCLIC PYRAZOLYL AND IMIDAZOLYL COMPOUNDS AS CANNABINOID RECEPTOR LIGANDS AND USES THEREOF | PFIZER PRODUCTS INC. (US) | 2005-07-07 | — | — | WO | disclosed |