Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626832 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1 | |
| SCHEMBL3626835 | 0.90 | ADRB2 (0.49) | ADRB2ADRB1 | |
| SCHEMBL4391611 | 0.88 | ADRB2 (0.62) | ADRB2ADRB1CHRM3 | |
| SCHEMBL4391614 | 0.88 | ADRB2 (0.62) | ADRB2ADRB1CHRM3 | |
| SCHEMBL3914423 | 0.85 | PARP1 (0.46) | ADRB2ADRB1PARP1 | |
| SCHEMBL13840706 | 0.85 | PARP1 (0.46) | ADRB2ADRB1PARP1 | |
| SCHEMBL5968674 | 0.83 | ADRB2 (0.59) | ADRB2ADRB1CHRM3 | |
| SCHEMBL5968828 | 0.83 | ADRB2 (0.59) | ADRB2ADRB1PARP1CHRM3 | |
| SCHEMBL5968825 | 0.83 | ADRB2 (0.59) | ADRB2ADRB1PARP1CHRM3 | |
| SCHEMBL5968677 | 0.83 | ADRB2 (0.59) | ADRB2ADRB1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005092841-A1 | COMPOUNDS HAVING BETA-AGONIST ACTIVITY | PFIZER LIMITED (GB) | 2005-10-06 | — | — | WO | disclosed |