Phenol

Phenol

SCHEMBL6534026

Cc1cc(O)c(C(C)(C)C)cc1Sc1cc(C(C)(C)C)c(O)cc1C.Oc1ccccc1

nearest known ligand 0.77

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.77
ALOX15 P16050 6/20 0.77
TP53 P04637 4/20 0.77
SMN1; SMN2 Q16637 3/20 0.77
TDP1 Q9NUW8 3/20 0.77
CYP3A4 P08684 3/20 0.77
TSHR P16473 2/20 0.77
MAPK1 P28482 1/20 0.77
HIF1A Q16665 1/20 0.77
CYP1A2 P05177 3/20 0.44
MAPT P10636 3/20 0.44
KDM4E B2RXH2 1/20 0.44
ATP2A2 P16615 1/20 0.44
ATP2A3 Q93084 1/20 0.44
CYP2C9 P11712 3/20 0.42
CYP2C19 P33261 3/20 0.42
CYP2D6 P10635 1/20 0.42
LMNA P02545 4/20 0.42
HSD17B10 Q99714 2/20 0.42
HTT P42858 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenol SCHEMBL1679670 1.00 ALDH1A1 (0.77) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL31295681 0.88 ALOX15 (1.00) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL39505 0.88 ALOX15 (1.00) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL29366086 0.88 ALOX15 (1.00) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL6553132 0.87 ALOX15 (0.77) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
Benzoic Acid SCHEMBL9771999 0.85 ALDH1A1 (0.60) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
Bicarbonate SCHEMBL11447857 0.85 ALOX15 (0.86) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL16281210 0.84 ALOX15 (0.77) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
SCHEMBL5014610 0.83 ALOX15 (0.71) ALDH1A1ALOX15TP53SMN1; SMN2TDP1
Formaldehyde SCHEMBL8818886 0.83 ALOX15 (0.89) ALDH1A1ALOX15TP53SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10008195-B2 Liquid rubber damping composition HENKEL AG & CO. KGAA (DE) 2018-06-26 US disclosed
EP-2954004-B1 LIQUID RUBBER DAMPING COMPOSITION HENKEL AG & CO KGAA (DE) 2018-06-20 EP disclosed
US-20160035339-A1 Liquid Rubber Damping Composition HENKEL AG & CO. KGAA (DE) 2016-02-04 US disclosed
EP-2954004-A1 LIQUID RUBBER DAMPING COMPOSITION Henkel AG&Co. KGAA (DE) 2015-12-16 EP disclosed
WO-2014124269-A1 LIQUID RUBBER DAMPING COMPOSITION HENKEL AG & CO. KGAA (DE) 2014-08-14 WO disclosed
EP-1074580-B1 A polyethylene crosslinkable composition UNION CARBIDE CHEM PLASTIC (US) 2005-10-26 EP disclosed
US-6187847-B1 HEAT RESISTANCE UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION 2001-02-13 US disclosed
EP-1074580-A2 A polyethylene crosslinkable composition UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2001-02-07 EP disclosed