⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2382629 | 1.00 | — | — | |
| SCHEMBL2888897 | 0.75 | — | — | |
| SCHEMBL10633964 | 0.72 | — | — | |
| SCHEMBL10633967 | 0.72 | — | — | |
| SCHEMBL8000999 | 0.69 | — | — | |
| SCHEMBL7760930 | 0.68 | FAAH (0.48) | — | |
| SCHEMBL7762387 | 0.68 | FAAH (0.48) | — | |
| SCHEMBL57531 | 0.67 | — | — | |
| SCHEMBL833539 | 0.67 | — | — | |
| SCHEMBL11424708 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520195-B | Novel nucleoside phosphonate prodrugs | 勒芬天主教大学 | 2023-01-17 | — | — | CN | disclosed |
| EP-2864312-B1 | NOVEL ANTI-CANCER THIOPHENE COMPOUNDS | UNIV LEUVEN KATH (BE) | 2021-09-22 | — | — | EP | disclosed |
| US-20210276988-A1 | 4,6-DI- AND 2,4,6-TRISUBSTITUTED QUINAZOLINE DERIVATIVES USEFUL FOR TREATING VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2021-09-09 | — | — | US | disclosed |
| US-11040047-B2 | Prodrugs of nucleoside phosphonates | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2021-06-22 | — | — | US | disclosed |
| US-10882851-B2 | 4,6-di- and 2,4,6-trisubstituted quinazoline derivatives useful for treating viral infections | GILEAD SCIENCES, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| EP-3600556-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | Katholieke Universiteit Leuven (BE) | 2020-02-05 | — | — | EP | disclosed |
| US-20190152974-A1 | SUBSTITUTED PTERIDINES USEFUL FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | GILEAD SCIENCES, INC. | 2019-05-23 | — | — | US | disclosed |
| EP-1581546-B1 | AVERMECTIN B1 DERIVATIVES HAVING AN ALKOXYMETHYL SUBSTITUENT IN THE 4''- OR 4'-POSITION | MERIAL INC (US) | 2019-03-20 | — | — | EP | disclosed |
| US-10144736-B2 | Substituted pteridines useful for the treatment and prevention of viral infections | GILEAD SCIENCES, INC. (US) | 2018-12-04 | — | — | US | disclosed |
| WO-2018172416-A1 | NOVEL PRODRUGS OF NUCLEOSIDE PHOSPHONATES | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2018-09-27 | — | — | WO | disclosed |
| WO-2002050052-A1 | N-ACYL AMINOACETONITRILES HAVING PESTICIDAL PROPERTIES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-06-27 | — | — | WO | disclosed |
| EP-1187818-A1 | PESTICIDALLY ACTIVE TETRAZINE DERIVATIVES | Syngenta Participations AG (CH) | 2002-03-20 | — | — | EP | disclosed |
| EP-1175410-A1 | PESTICIDAL TRIAZINE DERIVATIVES | Syngenta Participations AG (CH) | 2002-01-30 | — | — | EP | disclosed |
| WO-2002006243-A1 | TETRAHYDROPYRIMIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| WO-2002006252-A1 | ASYMMETRIC DIHYDROTRIAZINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| WO-2000078739-A1 | PESTICIDALLY ACTIVE TETRAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-12-28 | — | — | WO | disclosed |
| WO-2000066568-A1 | PESTICIDAL TRIAZINE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2000-11-09 | — | — | WO | disclosed |
| US-5234946-A | Anticholesterol, antilipemic | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-10 | — | — | US | disclosed |
| EP-0318860-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |