SCHEMBL6534548

SCHEMBL6534548

COC1(O)C=CC(C=CC(=O)c2ccccc2)=C(O)C1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
BCHE P06276 4/20 0.43
CYP3A4 P08684 4/20 0.43
RAB9A P51151 3/20 0.43
LMNA P02545 2/20 0.43
NFKB1 P19838 2/20 0.43
NFKB2 Q00653 2/20 0.43
RELA Q04206 2/20 0.43
NPC1 O15118 2/20 0.43
MAOB P27338 3/20 0.41
TNFRSF1A P19438 2/20 0.41
CYP1B1 Q16678 2/20 0.41
PLIN1 O60240 1/20 0.41
ACHE P22303 1/20 0.41
RECQL P46063 1/20 0.41
PLIN5 Q00G26 1/20 0.41
ABHD5 Q8WTS1 1/20 0.41
HSPD1 P10809 2/20 0.40
HSPE1 P61604 2/20 0.40
KMT2A Q03164 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27762378 0.86 MAPT (0.44) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL29945646 0.83 MAPT (0.46) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL6270921 0.83 MAPT (0.46) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL30385151 0.81 RECQL (0.43) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL28010219 0.81 RECQL (0.43) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL28984286 0.78 CYP3A4 (0.43) MAPTCYP3A4LMNAMAOBCYP1B1
SCHEMBL28721825 0.76 MAPT (0.44) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL1576591 0.75 TUBB4A (0.39) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL28796439 0.74 MAPT (0.42) MAPTBCHECYP3A4RAB9ALMNA
SCHEMBL7008154 0.74 PTPN1 (0.42) MAPTBCHECYP3A4RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004058213-A1 EXTRACT OF CERCIS CHINENSIS HAVING ANTI-OXIDANT ACTIVITY AND ANTI-AGING ACTIVITY, AND COSMETICAL COMPOSITION CONTAINING THE EXTRACT FOR ANTI-OXIDATION, SKIN-AGING PROTECTION AND WRINKLE IMPROVEMENT HANKOOK PHARM. CO., INC. (KR) 2004-07-15 WO claimed
WO-2004058213-A1 EXTRACT OF CERCIS CHINENSIS HAVING ANTI-OXIDANT ACTIVITY AND ANTI-AGING ACTIVITY, AND COSMETICAL COMPOSITION CONTAINING THE EXTRACT FOR ANTI-OXIDATION, SKIN-AGING PROTECTION AND WRINKLE IMPROVEMENT HANKOOK PHARM. CO., INC. (KR) 2004-07-15 WO disclosed