Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 9/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 0.76 |
| ▸ | NPC1 | O15118 | 4/20 | 0.76 |
| ▸ | CTSV | O60911 | 6/20 | 0.70 |
| ▸ | CTSL | P07711 | 6/20 | 0.70 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | TUBB | P07437 | 1/20 | 0.69 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.69 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.69 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.69 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.69 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.69 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.69 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.69 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411859 | 1.00 | HPGD (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11849112 | 0.89 | HPGD (0.80) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL2465149 | 0.86 | ALDH1A1 (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30462987 | 0.85 | HPGD (0.74) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26846971 | 0.84 | HPGD (0.72) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6534282 | 0.84 | HPGD (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6534320 | 0.84 | HPGD (0.79) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL26846955 | 0.83 | HPGD (0.71) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30935678 | 0.83 | HPGD (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6534180 | 0.83 | HPGD (1.00) | HPGDKDM4EALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240002348-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGN. OF SOC. ACT (ACT XXI OF 1860) (IN) | 2024-01-04 | — | — | US | disclosed |
| EP-4204410-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | Council of Scientific & Industrial Research, an Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) | 2023-07-05 | — | — | EP | disclosed |
| EP-1088818-B1 | Quinolin-4-yl derivatives | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6440995-B1 | NMDA-RECEPTOR SUBTYPE SELECTIVE BLOCKERS | HOFFMAN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-1088818-A1 | Quinolin-4-yl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240002348-A1 | QUINOLONE COMPOUNDS AND PROCESS FOR PREPARATION THEREOF | SQLE, NQO2, CYP1B1 | HPGD 316/4885KDM4E 112/4885ALDH1A1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.