Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.65 |
| ▸ | CTSV | O60911 | 1/20 | 0.62 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | TUBB | P07437 | 1/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.62 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.62 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.62 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.62 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.62 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6534282 | 0.88 | HPGD (1.00) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6534639 | 0.84 | HPGD (1.00) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL29411859 | 0.84 | HPGD (1.00) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL30462987 | 0.81 | HPGD (0.74) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL30462937 | 0.81 | HPGD (0.76) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL30935699 | 0.80 | HPGD (0.77) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL2630603 | 0.79 | HPGD (0.76) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL2465149 | 0.79 | ALDH1A1 (1.00) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL3699661 | 0.78 | KDM4E (0.77) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL31237652 | 0.78 | ALDH1A1 (0.82) | HPGDALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088818-B1 | Quinolin-4-yl derivatives | HOFFMANN LA ROCHE (CH) | 2004-11-03 | — | — | EP | disclosed |
| US-6440995-B1 | NMDA-RECEPTOR SUBTYPE SELECTIVE BLOCKERS | HOFFMAN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| EP-1088818-A1 | Quinolin-4-yl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2001-04-04 | — | — | EP | disclosed |
| WO-1994002145-A2 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 1994-02-03 | — | — | WO | disclosed |