SCHEMBL65347

SCHEMBL65347

C=C(C)C(=O)OC(C)Oc1cccc(OC(C)OC(=O)C(=C)C)c1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 7/20 0.41
MTNR1B P49286 7/20 0.41
ELANE P08246 1/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP3A4 P08684 1/20 0.36
LMNA P02545 1/20 0.36
OGG1 O15527 1/20 0.36
KDM4E B2RXH2 1/20 0.35
NSD2 O96028 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 1/20 0.35
PTGS1 P23219 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3157127 0.94 ELANE (0.44) MTNR1AMTNR1BELANERXRARXRB
SCHEMBL21370 0.90 MTNR1A (0.45) MTNR1AMTNR1BELANEMEN1KMT2A
SCHEMBL7564773 0.87 ELANE (0.41) MTNR1AMTNR1BELANEKMT2AALDH1A1
Methacrylic Acid SCHEMBL25394729 0.87 MTNR1A (0.43) MTNR1AMTNR1BELANEMEN1KMT2A
SCHEMBL28443934 0.84 PTGS1 (0.40) MTNR1AMTNR1BMEN1KMT2ALMNA
SCHEMBL7184057 0.84 MTNR1A (0.41) MTNR1AMTNR1BELANEMEN1KMT2A
SCHEMBL28149713 0.84 PPARG (0.44) ELANEMEN1KMT2ALMNAKDM4E
SCHEMBL10593821 0.83 KMT2A (0.42) MTNR1AMTNR1BMEN1KMT2ACYP3A4
SCHEMBL1264237 0.82 MTNR1A (0.42) MTNR1AMTNR1BELANEMEN1KMT2A
SCHEMBL10063818 0.82 MTNR1A (0.45) MTNR1AMTNR1BRXRARXRBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006340-A Methacrylate monomer, polymerization initiator, bactericide MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-04-09 US claimed
EP-0115709-B1 READILY CURABLE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-03-01 EP claimed
EP-0223245-A2 Curable compositions for dental drugs having sustained release property MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-27 EP claimed
EP-0115709-A2 Readily curable composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-08-15 EP claimed
US-8129443-B2 Inorganic oxide nanoparticles having an X-ray contrast property and high transparency, a functionalized silanediol monomeric or oligomeric surface modifier, and a polymerizable compound; dental composites SUN MEDICAL CO., LTD. (JP) 2012-03-06 US disclosed
US-20050123762-A1 Polymerizable composition, cured object obtained therefrom, and composite material SUN MEDICAL CO., LTD. (JP) 2005-06-09 US disclosed
EP-0136186-B2 Dental treatment composition curable by visible light MITSUI CHEMICALS INC (JP) 1999-03-03 EP disclosed
US-RE35135-E Dental material; mixture of radical-polymerizable monomer, alpha-ketocarbonyl and aromatic amine MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1995-12-26 US disclosed
EP-0266220-B1 CURABLE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-01-07 EP disclosed
US-5122061-A Two part composition of acrylate or methacrylate monomers, trialkylboron or oxide thereof; for dental composite resin MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-06-16 US disclosed
EP-0282280-B1 CURABLE ADHESIVE COMPOSITIONS MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-05-20 EP disclosed
EP-0323521-B1 CURABLE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-18 EP disclosed
EP-0136186-B1 PHOTOCURABLE RESIN COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-09-06 EP disclosed
EP-0323521-A1 CURABLE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-07-12 EP disclosed
US-4830616-A GLUTARALDEHYDE, FERRIC CHLORIDE, EDTA, ACRYLIC ESTER POLYMER, BONDING STRENGTH Okuda, Reiichi (JP) 1989-05-16 US disclosed
US-4826893-A POLYSILSESQUIOXANE-ACRYLIC ESTER COPOLYMER G-C DENTAL INDUSTRIAL CORP. (JP) 1989-05-02 US disclosed
US-4758643-A Dental adhesive resin compositions G-C DENTAL INDUSTRIAL CORP. (JP) 1988-07-19 US disclosed
EP-0266220-A2 Curable composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-05-04 EP disclosed
EP-0223245-A2 Curable compositions for dental drugs having sustained release property MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1987-05-27 EP disclosed
US-4548689-A RADICAL POLYMERIZABLE MONOMER, KETOCARBONYL COMPOUND AND MERCAPTOB MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1985-10-22 US disclosed